Soave incorporates various technologies into hybrid modes of artistic production. His computer works, lithographs, etchings, and silkscreen prints have been included in more than 120 regional, national, and international exhibitions in the past decade. Exhibitions include Matrix, at the FSU Art Museum, and Exploring Dreams, at the Arizona State University Museum, and a solo show at at the Diego Rivera Museum of Art in Guanajuato, Mexico. His works are included in collections of the Butler Museum of American Art, The Royal Museum of Antwerpen, Ohio University, Bradley University, and others. Residencies and lectures include Nanjing College of Fine Art, Beijing Academy of Fine Art, Universidad of Guanajuato, Frans Masereel Studio in Belgium, University of Georgia’s Cortona Program, Artists Image Resource in Pittsburgh, PA, and Peacock Printmaker’s Workshop in Scotland. Grants and fellowships include a Radiological Consultants Summer Fellowship, Canada Council Explorations Grant, West Virginia Artist Fellowship, and three West Virginia University Senate Research Grants. His work is represented in E.C. Cunningham's book on contemporary printmaking, Printmaking: A Primary Form of Expression and in Contemporary American Printmaking, published by Jilin Fine Arts Publishing of China.

Sergio Soave received his BFA from the University of Windsor and his MFA from West Virginia University (1987). Soave joined the WVU faculty in 1988 and served as department chair from 1997-2005. In August 2005, he became chair of the art department at The Ohio State University. In Columbus, he helped establish the OSU Urban Arts Space, an exhibition/community facility located in the downtown core. He also leads the OSU Public Arts Committee and is spearheading commissions of significant works by Ann Hamilton, Pae White, Chris Burden, and other noted artists.

Soave served as the President of the Southern Graphics Council, the largest, international, member organization, dedicated to printmaking, from 1996-1998. He also was a co-organizer for the 1996 SGC Conference, which drew more than 800 participants.